All-In with Chamath, Jason, Sacks & Friedberg

435 - Martin Shkreli: Big Pharma's Blind Spot, Betting Against Quantum & What Prison Taught Him

Industry veterans, degenerate gamblers & besties Chamath Palihapitiya, Jason Calacanis, David Sacks & David Friedberg cover all things economic, tech, political, social & poker.

More episodes

435 - Martin Shkreli: Big Pharma's Blind Spot, Betting Against Quantum & What Prison Taught Him

Mon, 12 Oct 2026
434 - Is Claude Conscious? Pope Rejects, Model Welfare Movement, OpenAI's Math Backlash, France Riots

Sat, 10 Oct 2026
433 - Trump's Super Intelligence Summit, AI Safety Accord, GDP Beats, Midterm Predictions

Fri, 02 Oct 2026
432 - Jake Paul & The Chainsmokers: Turning Fame into Funds, Jake Enters Politics? & Venture Bubble Signs

Wed, 30 Sep 2026
431 - Daniel Ek: Life After Spotify, Broken Healthcare Incentives, Catching Disease Early & AI's Potential

Mon, 28 Sep 2026
430 - Anthropic IPO at Risk, Meta's Muse Pop, Token Prices Fall, Open Source Gains Share, Alignment Fails

Sat, 26 Sep 2026
429 - Luca Ferrari, Bending Spoons CEO: The $40K Origin Story, Buying Product-Market Fit & Why Private Equity Can't Compete

Wed, 23 Sep 2026
428 - Steve Hilton & Spencer Pratt: Fixing California, Cheaper Gas, Ballot Fraud & CA Republicans

Wed, 23 Sep 2026
427 - Blake Scholl: Why Plane Speed Stalled, Supersonic Commercial Flight, & Revolutionizing the Engine

Tue, 22 Sep 2026
426 - Naveen Rao: 4D Computing, AI's Energy Wall & Beating Biology

Mon, 21 Sep 2026
425 - Adam Foroughi, Applovin CEO: Surviving a 92% Drawdown, Ads as ML 1.0 & the $50B Game Ad Market

Sun, 20 Sep 2026
424 - Bill Gurley: Searching for Feynman

Sat, 19 Sep 2026
423 - Jared Isaacman: A New Era for NASA and American Space Exploration

Fri, 18 Sep 2026
422 - Nick Shirley: Exposing Government Fraud, Suing California & Taking on the Media

Fri, 18 Sep 2026
421 - Meta's Dina Powell McCormick: The Case for Data Centers, Backlash, AI Job Boom & Meta's Future

Thu, 17 Sep 2026
420 - Brad Gerstner: No AI Bubble, Semis Eat the Nasdaq & AI's Take Off Problem

Thu, 17 Sep 2026
419 - JD Vance on AI, Entitlement Fraud, Iran War, Israel, H-1B Abuse & the Midterms

Tue, 15 Sep 2026
418 - Satya Nadella on the AI Doomer Slowdown, Microsoft's Master Plan & Who Wins AI

Tue, 15 Sep 2026
417 - Elon Musk & Gwynne Shotwell on AI Risks and Peer Review, Starship, Terafab, SpaceX/Tesla Merger

Tue, 15 Sep 2026
416 - Jensen Huang: The Doomer Hoax, Superintelligence Is Here, and The Future of AI (ft. President Trump)

Mon, 14 Sep 2026
415 - AI Kills Everybody or Doomer Psyop? OpenAI's Math Breakthrough, Nike's $200B Collapse

Fri, 11 Sep 2026
414 - GPT-6 Hits AGI? Tech Euphoria 2.0, SF Mansion Shortage, NYC Bans AI in Schools & Venezuela Oil Deal

Fri, 04 Sep 2026
413 - Nvidia's Historic Quarter, SaaS Comeback, Bessent vs Druck, America's Debt Crisis, Cancer Vaccine

Sat, 29 Aug 2026
412 - Eric Weinstein: The State of American Science, Breakthrough Coverups, and the Danger of Physics

Wed, 26 Aug 2026
411 - Michael Kratsios: Trump's Science Agenda, Anti-Science Claims, Fauci's Damage, DEI & China

Mon, 24 Aug 2026
410 - Dario Defends Himself, Datacenter Panic, AI Doomer Trap, Senate Toss-Up

Fri, 21 Aug 2026
409 - Flock CEO Garrett Langley on Controversy, "Surveillance State" Claims, and Privacy vs Safety

Tue, 18 Aug 2026
408 - Anthropic's $2T IPO, Zuck's AI Manifesto, Nvidia's $500B AI Bet, Grok's Comeback

Fri, 14 Aug 2026
407 - Rahm Emanuel: Trump's Foreign Policy, China, Europe's Decline, Immigration & DSA vs Democrats

Thu, 13 Aug 2026
406 - Google's AI Brain Drain, SpaceX's Huge Quarter, Airtable's 90% Collapse, US Data Fuels China AI

Sat, 08 Aug 2026
405 - Saronic Founders: Autonomous Warships, China's 230X Advantage & Swarms of Robot Ships

Wed, 05 Aug 2026
404 - Chip Stocks Crash, $20B Fund Margin Called, Frontier Labs: SLOW DOWN AI, Mamdani's Grocery Stores

Fri, 31 Jul 2026
403 - The $1/Hour Worker: Four Robotics CEOs on Humanoids at Home, China's Threat, and the End of Dangerous Jobs

Tue, 28 Jul 2026
402 - The Fight Over Open Source AI, Anthropic's $1.5B Payout, NYC Socialists: Evictions = Violence?

Fri, 24 Jul 2026
401 - Mark Cuban on the AI Bubble: Who Actually Gets Wiped Out?

Mon, 20 Jul 2026
400 - Can the AI Industry Regulate Itself? Stripe Wants PayPal, China Catches Up, NY Bans Datacenters

Sat, 18 Jul 2026
399 - Former Intel CEO on What Went Wrong, What's Next + Lovable CEO on the Real Promise of Vibe Coding

Wed, 15 Jul 2026
398 - The Trillion-Dollar Industries AI Is Disrupting: Voice, Law & the End of the Billable Hour

Mon, 13 Jul 2026
397 - More Trillion Dollar IPOs, Anthropic $3T, Zuck's Price War, China Ends Open Source?, Trump Accounts

Sat, 11 Jul 2026
396 - Open Source Wins, AGI Is Here, and Scorsese's AI Toolkit with CEOs of Cerebras & Black Forest Labs

Fri, 10 Jul 2026
395 - AI Sovereignty Wars, Palantir-Nvidia Deal, SCOTUS Birthright Ruling, Newsom's CA Budget Lie

Fri, 03 Jul 2026
394 - Nate Silver Predicts: Democrats Take the House, Newsom Is Fading & AOC Might Win It All in 2028

Mon, 29 Jun 2026
393 - Socialists Sweep NYC, China Catches Up in Coding, AI Memory Crunch, Micron's Blowout Quarter

Fri, 26 Jun 2026
392 - GameStop CEO Ryan Cohen's $56B Plan to Take Over eBay

Tue, 23 Jun 2026
391 - World's First Trillionaire, Anthropic Fable Banned, The New Oligarchs, Iran Peace Deal

Fri, 19 Jun 2026
390 - Anthropic's Fable Backlash, Nationalizing AI, Inflation Heats Up & California's Broken Elections

Sat, 13 Jun 2026
389 - All-In's Best Ideas Pitch Competition: 4 Investors Present Their Top Trades Live

Fri, 12 Jun 2026
388 - Senators John Fetterman and Dave McCormick: Bipartisanship, Money in DC, Datacenters, Graham Platner

Wed, 10 Jun 2026
387 - Dan Dreyfus: America's Critical Minerals Crisis is Here

Wed, 10 Jun 2026
386 - Bill Maris: How Google Could Crush AI Competitors, Why Small Funds Win, and AI's Atari Stage

Tue, 09 Jun 2026